Cornea
Terrien Marginal Degeneration
Also known as: TMD, Terrien degeneration, peripheral corneal thinning, superior corneal thinning, against-the-rule astigmatism, non-inflammatory corneal thinning, marginal corneal degeneration, peripheral corneal degeneration
Clinical decision support only
Overview
A rare peripheral corneal thinning degeneration, classically superior or superior-nasal, with an intact epithelium, superficial vascularisation, lipid deposition at the leading edge, and progressive against-the-rule or irregular astigmatism. It is usually non-inflammatory or minimally inflammatory. The key safety task is to separate Terrien marginal degeneration from active inflammatory or ulcerative disease such as peripheral ulcerative keratitis, Mooren ulcer, marginal keratitis, infectious keratitis, pellucid marginal degeneration, keratoconus, or keratoglobus.
What OptoGuide™ covers for terrien marginal degeneration
- Recognition patterns — symptoms, signs, and differentiators
- Don't-miss risks and escalation triggers
- Management tiers with linked Australian therapeutics
- Referral urgency, specialty, and letter drafting
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