Cornea
Contact Lens Peripheral Ulcer
Also known as: CLPU, contact lens peripheral ulcer, CL peripheral ulcer, contact lens infiltrate, peripheral corneal infiltrate contact lens, sterile corneal infiltrate CL, CL ulcer, contact lens keratitis peripheral
Clinical decision support only
Overview
A sterile inflammatory corneal infiltrate at the peripheral or paracentral cornea associated with contact lens wear. Caused by an immune response to bacterial toxins (typically Staphylococci or Gram-negative organisms) or inflammatory mediators, rather than true infection. Distinct from microbial keratitis: CLPU infiltrates are typically small (< 1mm), peripheral, with minimal or no staining, and occur with lens wear — not a true corneal infection.
What OptoGuide™ covers for contact lens peripheral ulcer
- Recognition patterns — symptoms, signs, and differentiators
- Don't-miss risks and escalation triggers
- Management tiers with linked Australian therapeutics
- Referral urgency, specialty, and letter drafting
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