Cornea

Neurotrophic keratopathy

Also known as: neurotrophic keratitis, neurotrophic cornea, reduced corneal sensation, anaesthetic cornea, persistent epithelial defect, non-healing epithelial defect, post herpetic neurotrophic keratopathy

Clinical decision support only

OptoGuide™ supports professional judgement and does not diagnose or replace clinician responsibility.

Overview

Corneal epithelial breakdown caused by impaired trigeminal innervation and reduced corneal sensation. Symptoms may be deceptively mild despite persistent epithelial defect, ulceration, stromal thinning, infection risk, or perforation. Optometry management is recognition, corneal sensation testing, epithelial risk assessment, surface protection, and urgent ophthalmology/cornea referral when epithelial compromise is present.

What OptoGuide™ covers for neurotrophic keratopathy

Recognition patterns — symptoms, signs, and differentiators
Don't-miss risks and escalation triggers
Management tiers with linked Australian therapeutics
Referral urgency, specialty, and letter drafting

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