Cornea
Marginal Keratitis
Also known as: marginal keratitis, staphylococcal marginal keratitis, peripheral corneal infiltrate, blepharitis keratitis, catarrhal ulcer, marginal ulcer, staphylococcal hypersensitivity keratitis, peripheral corneal opacity
Clinical decision support only
OptoGuide™ supports professional judgement and does not diagnose or replace clinician responsibility.
Overview
A delayed hypersensitivity reaction (Type IV) to Staphylococcal exotoxins from chronic staphylococcal blepharitis. Presents as peripheral corneal infiltrates separated from the limbus by a clear zone. Common in patients with chronic lid margin disease. Distinct from bacterial keratitis — the infiltrates are sterile and stain minimally or not at all with fluorescein.
What OptoGuide™ covers for marginal keratitis
- Recognition patterns: symptoms, signs, and differentiators
- Don't-miss risks and escalation triggers
- Management tiers with linked Australian therapeutics
- Referral urgency, specialty, and letter drafting